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Granny is a first-person horror survival game developed by DVloper that has captivated the attention of players worldwide with its nerve-wracking atmosphere, unique gameplay, and terrifying antagonist — the titular character, Granny. Released for mobile devices and later adapted for PC platforms, the game challenges players to escape from a locked house within five days, all while avoiding the relentless pursuit of a horrifying old woman with heightened hearing. With simple graphics but immersive sound design and gameplay mechanics, "Granny" has become a cult classic in the mobile horror genre.

Cysteine Conjugation and Lysine Conjugation are two commonly used pathways in the bioconjugation of antibodies, proteins, drugs, probes, and other biomolecules. They utilise the thiol group of cysteine and the ε-amino group of lysine as starting points, respectively, to achieve stable covalent bonds on the antibody surface through different chemical reactions. Understanding their respective mechanisms, advantages, disadvantages, and application scenarios can help in designing more precise labelling strategies.

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